Best Medical Billing Software of 2025: Analysis and Comparison

Best Medical Billing Software of 2025: Analysis and Comparison

Given the overwhelming choices, healthcare practices looking for the best medical billing software will likely encounter decision challenges. Also, many software solutions overlap in features, while others lack the scalability your business needs to sustain growth.

Here’s our 2025 list of top software used for medical billing.

1. EHR Your Way

Best Medical Billing Software of 2025: Analysis and Comparison

EHR Your Way has been around since 2008, making a name for itself as one of the top-rated electronic medical billing software designed for behavioral health agencies with 15 or more users. Aside from patient intake, clinical notes, reporting, and patient portal, the EHR also offers billing. If you’ve ever experienced losing money because of incorrect or failed billing, EHR Your Way can help solve your problem.

Top Features:

  • Create claims automatically at check-in or when notes are completed
  • Auto-check insurance eligibility
  • Send bills to clearinghouses
  • Create real-time billing reports
  • Review the patient ledger
  • Automatically check claims for errors
  • Tailor the list of CPT codes to match your services
  • Accept credit card payments online
  • Use the API to build your own apps and connect with third party apps

2. Jane

Best Medical Billing Software of 2025: Analysis and Comparison

Jane EHR is one of the trusted medical billing software programs for Canadian, U.S., and U.K. users. Users attest to premium client support, a well-designed interface, and consistent improvements.  We love the platform’s clean and organized look, a far cry from some EHR brands that look too complex and intimidating. Jane is an all-around EHR offering online booking, staff and admin scheduling, documentation, online appointments, and hospital billing.

Top Features: 

  • Generate insurance invoices
  • Gather insurance policies before the patient visit, confirming each appointment is insured
  • Send the remaining bill to the patient’s secondary or tertiary insurance policies
  • Reuse insurance details from a patient’s previous visit
  • Handle different insurance payment methods
  • Submit and track claims within Jane
  • Reverse or correct accidental claim submissions
  • Sync with your website

3. ChiroFusion

Best Medical Billing Software of 2025: Analysis and Comparison

Are you a chiropractor? ChiroFusion is one of the top medical billing software for chiropractic practices. An all-in-one EHR, ChiroFusion also includes appointment management, claims management, claims scrubbing, charting, and insurance eligibility verification. The company claims that its team of certified billers and users are all based in the U.S., unlike other services that send accounts overseas. Best of all, users attest that customer service is top-notch.

Top Features: 

  • Ensure accurate entry of insurance IDs, claims addresses, and other information
  • Record insurance payments and reconcile with bank deposit slips
  • Automatically handle insurance carrier issues and follow up on unpaid claims
  • Match chiropractic CPT codes to diagnosis codes
  • Analyze and resolve denial issues
  • Gather eligibility information before patient visits

4. ClinicSense

Best Medical Billing Software of 2025: Analysis and Comparison

ClinicSense provides a complete EHR  with invoicing and payment features. The EHR is easy to use and reasonably priced, which is a huge help for individual practitioners looking to digitize their medical billing process.  Certain features are missing, like auto-collection of credit card information upon booking. However, ClinicSense is one of the most budget-friendly options for those with minimal billing requirements.

Top Features:

  • Automatically create invoices with each appointment
  • Choose from different payment methods
  • Split payments between payment methods
  • Email or print receipts for clients
  • Send unpaid invoices through email
  • Integrate with Square, Stripe, Instagram, and Meta for Business

5. Elation Health

Best Medical Billing Software of 2025: Analysis and Comparison

Elation Health is one of the best cloud based medical billing software for its ease of use and setup. The layout is intuitive and logical for healthcare practitioners, and the platform works efficiently. It also integrates fax services, so users can quickly send off documents securely. If you need billing software to help you collect payments, consider Elation Health.

Top Features:

  • Send automated appointment reminders via SMS and email
  • Verify insurance coverage in real-time
  • Collect payments and manage authorizations in one platform
  • Automatically transfer procedure and diagnosis codes from patient charts to bills
  • Offer flexible payment plans and electronic statements
  • Download customizable and exportable financial reports
  • Review and correct insurance claims
  • Use the API to build your own apps and connect with third party apps

6. SimplePractice

Best Medical Billing Software of 2025: Analysis and Comparison

One of the trusted online medical billing software, SimplePractice helps you send paperless insurance forms, automated invoices and billing, and intakes through its platform. Customers attest to easy documentation, simple navigation, and comprehensive features. However, it could be more expensive than other EHRs and includes an additional cost for electronic claim filing and insurance coverage reports.

Top Features:

  • Receive online payments
  • Store credit card information
  • Generate superbills
  • Send automated invoices
  • File electronic claims
  • Create insurance coverage reports
  • PCI-compliant

7. Tebra

Best Medical Billing Software of 2025: Analysis and Comparison

You might come across other medical billing software online reviews talking about Kareo or PatientPop. In 2021, these two software merged to become Tebra. Tebra now combines practice management and medical billing, even integrating with other electronic health records software to help you run administrative tasks efficiently.  

Top Features:

  • Track tasks and payments
  • Check for insurance eligibility
  • File insurance claims
  • Send electronic claims
  • Receive automated payments from numerous payment channels
  • Send text and email reminders to patients
  • Interact with third party apps using Tebra SOAP API

8. TheraNest

Best Medical Billing Software of 2025: Analysis and Comparison

Geared toward mental health professionals, TheraNest makes it to our list of best software for medical billing. Insurance claims and payment collections can be a headache, but TheraNest promises to be a cure with its simplicity, flexibility, and scalability. If you don’t have time to manage billing tasks, TheraNest can help with most of them.

Top Features:

  • Validate and submit insurance claims
  • Correct and follow up on rejected claims
  • Track insurance billing remittances
  • Create, print, and email invoices and superbills
  • Charge multiple credit cards at the same time
  • Accept credit card payments through a mobile friendly Client Portal
  • Save credit card information
  • Process ERA/EOB files automatically
  • Generate daily billing reports
  • Check CPT Codes and CPT Code modifiers

9. AthenaOne

Best Medical Billing Software of 2025: Analysis and Comparison

AthenaOne in all-in one user-friendly software used for medical billing and coding. The platform lets you see your claims- and appointment-related activities in one dashboard, ensuring you won’t lose track of billing tasks. However, some reviews say it may be daunting to use because of its comprehensive features.  If you need medical billing software with advanced features yet scalable to small practices, check AthenaOne. 

Top Features:

  • Analyze and resolve claim issues before submission
  • HIPAA-compliant, AAPC/AHIMA certified, and third party audited coding team
  • Send detailed notes for a coder’s review
  • Get same- or next-day authorizations for situations needing immediate care
  • Receive automated alerts about patient eligibility issues before an appointment
  • Generate performance reports
  • Use the API to integrate apps and EHR faxing into billing workflows

10. DrChrono

Best Medical Billing Software of 2025: Analysis and Comparison

If you’re looking for software used for medical billing and coding, don’t leave out DrChrono. The practice management platform includes features that help you collect payments faster and manage administrative tasks efficiently. Created by EveryHealth, DrChrono is built for independent health practices looking for a complete EHR.

Top Features:

  • View billing reports and analytics
  • Create billing profiles and custom billing codes
  • Check insurance eligibility in real-time
  • Look up over 73,000 ICD-10, DSM5 and CPT billing codes
  • Submit claims to iHCFA for workers comp and auto claims
  • Submit claims via eProvider solutions
  • Autopost electronic remittance advice
  • Autogenerate superbills and CMS 1500 forms
  • Create apps using DrChrono API

Factors to Consider When Choosing Medical Billing Software

When choosing medical billing software, consider the following factors:

  • Scalability – Can the platform’s features adjust to the needs of my business? What if I need to reduce or increase features?
  • Cost – Will it fit my budget? Does it offer a monthly plan, free trial, or discount?
  • Ease of use – Is the software clunky or too complicated to use? Does the company offer training?
  • Customer service – Does the company respond quickly when I need help? What channels do they offer for their customers to easily reach them?
  • HIPAA compliance – Does the company sign a business associate agreement?
  • Integration – Does the medical billing software integrate with other apps that you use? Can you connect it to your website?

Fax From the Best Medical Billing Software With iFax

Faxing from the top medical billing software can help you run your practice more efficiently. Imagine, you won’t have to run to a physical fax machine or open another online app to send your documents. iFax is best for integrating faxing with any medical billing software.

Using the iFax Fax API, you can easily fax from any of the top medical billing software. Best of all, faxing is always secure in iFax. Our platform complies with HIPAA and provides a BAA, ensuring that your patient’s medical information stays safe.

Request a free demo to learn how to fax from any medical billing software using iFax.

Kent CaƱas

Kent is a content strategist currently specializing in HIPAA-compliant online fax. Her expertise in this field allows her to provide valuable insights to clients seeking a secure and efficient online fax solution.

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